Endocrine Abstracts

Introduction: Adrenal insufficiency is rarely diagnosed during pregnancy. In the absence of treatment it is associated with high maternal-foetal morbidity and mortality. We report the case of a twenty-one years old female patient, diagnosed with adrenal insufficiency during a diabetic pregnancy of 12 weeks of gestation.Observation: Twenty-one years old female patient, diagnosed with type 1 diabetes since the age of 15, Referred to our department for the ...

Graves’ disease is a rare and severe disease that most often affects older children and is predominantly female. The diagnosis is made in the presence of a clinical picture very suggestive of thyrotoxicosis, confirmed by biological and radiological tests. We present the case of an 11-year-old female patient who presented with a moderate presented of basedow with an ultrasound appearance of thyroiditis for which scintigraphy was helpful in the diagnosis. Female patient, 11...

Introduction: Type 2 diabetes is an important risk factor for all forms of infection. It may be unrecognised for many years, and often revealed by degenerative or infectious complications. The aim of this study is to investigate the epidemiological, clinical and therapeutic aspects of severe infections revealing type 2 diabetes.Patients and Methods: Retrospective descriptive cross-sectional study of a series of 5 patients with severe infections revealing...

Introduction: Cushing disease is the most common cause of endogenous hypercortisolism. Pituitary surgery is the first-line treatment and bilateral adrenalectomy is the option of last resort due to its severe consequences.Observation: This is a 24-year-old patient followed for cushing disease revealed by a severe cushing syndrome, a urinary cortisol at 20 times normal and negative dexamethasone suppression test with a pituitary microadenoma on MRI. He was...

Introduction: Polyuro-polydipsia syndrome (PPS) is defined by urine excretion rate more than 3L per day, associated with a parallel increase in oral fluid intake. It poses problems of positive and etiological diagnosis. We discuss in this observation the modalities of exploration of PPS and its main etiologies.Case report: A 60-year-old patient, diabetic for 10 years, controlled on metformin, admitted for PPS evolving for 37 years. Clinical examination w...

Introduction: Wernicke’s encephalopathy is a rare neurological disorder initially described in alcohol-dependent and malnourished patients. It is characterised by confusion, ataxia and nystagmus. It is caused by thiamine deficiency. We report the case of a patient with hyperemesis gravidarum and hashitoxicosis complicated by Wernicke’s encephalopathy Observation: A 22 year old patient, 1G0P, without any particular pathological history, was admi...

Introduction: The non-Hodgkin lymphomas (NHL) involve extralymphatic sites more often than does Hodgkin lymphoma; consequently, tumor involvement of almost every abdominal organ has been recorded. Adrenal involvement in patients with NHL may be present at the time of initial assessment. however, adrenal insufficiency as a consequence of adrenal invasion is rare. We report a case of a patient diagnosed with NHL with breast and bilateral adrenal involvement.<p class="abstext...

Introduction: MODY (maturity-onset diabetes of the young) is a group of heterogeneous diabetic disorders characterized by dysfunction of insulin secretion by the β-cell and genetically transmitted. MODY diabetes is thought to account for 2-5% of all diabetic disorders, but is often under-diagnosed. We report two suspected cases of MODY diabetes.Observations: Case 1: 40-year-old patient, known diabetic for 3 years, initially on Gliclazide 60 mg and M...

Introduction: Hypoglycemia is a common medical emergency, occurring more frequently in diabetic patients. Rarely induced by a tumor cause, but it is important to recognize the syndrome when it occurs. We report the case of a 64-year-old female patient presenting with hypoglycemia on pancreatic tumor complicated by bilithorax.Observation: 64-year-old female patient, known diabetic for 1 year on Glimeperide 3 mg and Metformin 1 g, hypertension for 1 year o...

Introduction: Thyroid-gastric autoimmune syndrome (TGS), described in the 1960s, is the autoimmune association of thyroid disease (Hashimoto’s or Graves’ disease) and gastric mucosal disease (Biermer’s disease) in the same patient. Although this association is part of the autoimmune polyendocrinopathies, its prevalence is largely underestimated in the literature. We report the case of a 56-year-old female patient with TGS.Observation: Pati...